Uncommon Anal Neoplasms

Amitesh C. Roy, David Wattchow, David Astill, Simron Singh, Susan Pendlebury, Kirsten Gormly, Eva Segelov

    Research output: Contribution to journalReview articlepeer-review

    11 Citations (Scopus)


    Anal cancer is a rare disease with epidermoid cancers accounting for 1% to 2% of all digestive tract malignancies.1Less common anal neoplasms comprise approximately 20% to 25% of these,2including anal canal adenocarcinoma, anorectal melanoma,mesenchymal and neurogenic tumors of the anal canal (in particular gastrointestinal stromal tumors [GIST], schwannomas, and sarcomas), neuroendocrine tumors (NETs),lymphoma, and basal cell carcinoma (BCC). The anal canal is also a rare site for metastasis from other primary malignancies. As imaging technology improves, particularly MRI, and colonoscopy becomes routine, many rarer tumors are detected incidentally.Diligent linkage of clinical features with expert histopathology assessment identifies uncommon anal neoplasms to ensure that appropriate management is instituted.
    Original languageEnglish
    Pages (from-to)143-161
    Number of pages19
    JournalSurgical Oncology Clinics of North America
    Issue number1
    Publication statusPublished - Jan 2017


    • Anal lymphoma
    • Anal melanoma
    • Anal neuroendocrine tumor
    • Unusual cancers


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