Unexpected vitamin K deficiency in hospitalized patients

G. F. Pineo, A. S. Gallus, J. Hirsh

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)


Twenty-seven patients developed vitamin K deficiency unexpectedly in the postoperative period or during hospitalization for a variety of medical conditions. Twenty-two of the patients were on antibiotics. Nineteen were on no oral intake during part of their hospital stay, and the remainder had a poor food intake. Fifty percent developed vitamin K deficiency within seven days. It is suggested that the rapid onset of vitamin K deficiency in these patients may have been due to a combination of the use of multiple antibiotics and poor food intake.
Original languageEnglish
Pages (from-to)880-883
Number of pages4
JournalCanadian Medical Association Journal
Issue number9
Publication statusPublished - 3 Nov 1973
Externally publishedYes


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