TY - JOUR
T1 - Update on the global burden of ischemic and hemorrhagic stroke in 1990-2013
T2 - The GBD 2013 study
AU - Feigin, Valery L.
AU - Krishnamurthi, Rita V.
AU - Parmar, Priya
AU - Norrving, Bo
AU - Mensah, George A.
AU - Bennett, Derrick A.
AU - Barker-Collo, Suzanne
AU - Moran, Andrew E.
AU - Sacco, Ralph L.
AU - Truelsen, Thomas
AU - Davis, Stephen
AU - Pandian, Jeyaraj Durai
AU - Naghavi, Mohsen
AU - Forouzanfar, Mohammad H.
AU - Nguyen, Grant
AU - Johnson, Catherine O.
AU - Vos, Theo
AU - Meretoja, Atte
AU - Murray, Christopher J.L.
AU - Roth, Gregory A.
AU - GBD 2013 Writing Group
AU - GBD 2013 Stroke Panel Experts Group
AU - Abd-Allah, Foad
AU - Abera, Semaw Ferede
AU - Akinyemi, Rufus Olusola
AU - Salman, Rustam Al Shahi
AU - Anderson, Craig S.
AU - Bahit, Maria Cecilia
AU - Banerjee, Amitava
AU - Basu, Sanjay
AU - Beauchamp, Norman J.
AU - Bornstein, Natan M.
AU - Brainin, Michael
AU - Cabral, Norberto Luiz
AU - Campos-Nonato, Ismael
AU - Caso, Valeria
AU - Catalá-López, Ferrán
AU - Chowdhury, Rajiv
AU - Christensen, Hanne K.
AU - Connor, Myles D.
AU - DeVeber, Gabrielle
AU - Dharmaratne, Samath D.
AU - Dokova, Klara
AU - Donnan, Geoffrey
AU - Endres, Matthias
AU - Fernandes, Jefferson Gomes
AU - Gankpé, Fortuné
AU - Geleijnse, Johanna M.
AU - Gillium, Richard F.
AU - Giroud, Maurice
AU - Hamadeh, Randah R.
AU - Hankey, Graeme J.
AU - Jeemon, Panniyammakal
AU - Jonas, Jost B.
AU - Kazi, Dhruv S.
AU - Kengne, Andre Pascal
AU - Kim, Daniel
AU - Kissela, Brett M.
AU - Kokubo, Yoshihiro
AU - Kosen, Soewarta
AU - Kravchenko, Michael
AU - Lavados, Pablo M.
AU - Liu, Ming
AU - Lotufo, Paulo A.
AU - MacKay, Mark T.
AU - Malekzadeh, Reza
AU - Mehndiratta, Man Mohan
AU - Melaku, Yohannes Adama
AU - Misganaw, Awoke
AU - Nand, Devina
AU - Piradov, Michael
AU - Pourmalek, Farshad
AU - Rojas-Rueda, David
AU - Roy, Nobhojit
AU - Sahathevan, Ramesh
AU - Sampson, Uchechukwu K.A.
AU - Shamalov, Nikolay
AU - Sheth, Kevin N.
AU - Shinohara, Yukito
AU - Shiue, Ivy
AU - Soljak, Michael
AU - Sposato, Luciano A.
AU - Stroumpoulis, Konstantinos
AU - Tanne, David
AU - Thrift, Amanda G.
AU - Tirschwell, David Lawrence
AU - Varakin, Yuri
AU - Venketasubramanian, Narayanaswamy
AU - Vlassov, Vasiliy Victorovich
AU - Wang, Wenzhi
AU - Westerman, Ronny
AU - Wolfe, Charles
AU - Yu, Chuanhua
AU - Yunjin, Kim
AU - Stavreski, Bill
AU - Pearse, Edwin
AU - Ademi, Zanfina
AU - Guliyev, Tural
AU - Harewood, Heather
AU - Springer, Karen
AU - Da Costa Leite, Iuri
AU - Lindsay, M. Patrice
AU - Riccio, Patricia M.
AU - Li, Bin
AU - Jiang, Guohong
AU - Ma, Jixiang
AU - Zhou, Maigeng
AU - Zhu, Shankuan
AU - Liang, Xiaofeng
AU - Zhang, Yong
AU - Alcalá-Cerra, Gabriel
AU - Temesgen, Awoke
AU - Sahle, Berhe Weldearegawi
AU - Prabhakaran, Dorairaj
AU - Gupta, Rajeev
AU - Rajagopalan, Vasanthan
AU - Warouw, Tati Suryati
AU - O'Donnell, Martin J.
AU - Ricci, Stefano
AU - Asad, Majed Masoud
AU - Bwire, Vitalis Kizito
AU - Jee, Sun Ha
AU - Khang, Young Ho
AU - Myint, Chaw Yin
AU - Norheim, Ole
AU - Khalifa, Shams Eldin
AU - De Dieu Ngirabega, Jean
AU - Nyemazi, Jean Pierre
AU - Muhimpundu, Marie Aimee
AU - Saeedi, Mohammad
AU - Bedi, Neeraj
AU - Havmoeller, Rasmus
AU - Atwine, Leo
AU - O'Callaghan, Finbar
AU - Critchley, Julia A.
AU - Ezzati, Majid
AU - Rothwell, Peter M.
AU - Whiteley, William
AU - Chen, Zhengming
AU - Colomar, Mercedes
AU - Durrani, Adnan M.
AU - Dayama, Anand
AU - Amlie-Lefond, Catherine
AU - Huang, Cheng
AU - Sumeet, Chugh
AU - Cundiff, David K.
AU - Qato, Dima
AU - Kabagambe, Edmond Kato
AU - Ding, Eric
AU - Bukhman, Gene
AU - Kwan, Gene
AU - Thurston, George
AU - Coresh, Josef
AU - Lefondulq, Kate
AU - Corriere, Matthew A.
AU - Mainoo, Nana
AU - Schwartz, Stephen M.
AU - Fung, Teresa
AU - Byers, Tim E.
AU - Rocca, Walter A.
AU - Lo, Warren
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Background: Global stroke epidemiology is changing rapidly. Although age-standardized rates of stroke mortality have decreased worldwide in the past 2 decades, the absolute numbers of people who have a stroke every year, and live with the consequences of stroke or die from their stroke, are increasing. Regular updates on the current level of stroke burden are important for advancing our knowledge on stroke epidemiology and facilitate organization and planning of evidence-based stroke care. Objectives: This study aims to estimate incidence, prevalence, mortality, disability-adjusted life years (DALYs) and years lived with disability (YLDs) and their trends for ischemic stroke (IS) and hemorrhagic stroke (HS) for 188 countries from 1990 to 2013. Methodology: Stroke incidence, prevalence, mortality, DALYs and YLDs were estimated using all available data on mortality and stroke incidence, prevalence and excess mortality. Statistical models and country-level covariate data were employed, and all rates were age-standardized to a global population. All estimates were produced with 95% uncertainty intervals (UIs). Results: In 2013, there were globally almost 25.7 million stroke survivors (71% with IS), 6.5 million deaths from stroke (51% died from IS), 113 million DALYs due to stroke (58% due to IS) and 10.3 million new strokes (67% IS). Over the 1990-2013 period, there was a significant increase in the absolute number of DALYs due to IS, and of deaths from IS and HS, survivors and incident events for both IS and HS. The preponderance of the burden of stroke continued to reside in developing countries, comprising 75.2% of deaths from stroke and 81.0% of stroke-related DALYs. Globally, the proportional contribution of stroke-related DALYs and deaths due to stroke compared to all diseases increased from 1990 (3.54% (95% UI 3.11-4.00) and 9.66% (95% UI 8.47-10.70), respectively) to 2013 (4.62% (95% UI 4.01-5.30) and 11.75% (95% UI 10.45-13.31), respectively), but there was a diverging trend in developed and developing countries with a significant increase in DALYs and deaths in developing countries, and no measurable change in the proportional contribution of DALYs and deaths from stroke in developed countries. Conclusion: Global stroke burden continues to increase globally. More efficient stroke prevention and management strategies are urgently needed to halt and eventually reverse the stroke pandemic, while universal access to organized stroke services should be a priority.
AB - Background: Global stroke epidemiology is changing rapidly. Although age-standardized rates of stroke mortality have decreased worldwide in the past 2 decades, the absolute numbers of people who have a stroke every year, and live with the consequences of stroke or die from their stroke, are increasing. Regular updates on the current level of stroke burden are important for advancing our knowledge on stroke epidemiology and facilitate organization and planning of evidence-based stroke care. Objectives: This study aims to estimate incidence, prevalence, mortality, disability-adjusted life years (DALYs) and years lived with disability (YLDs) and their trends for ischemic stroke (IS) and hemorrhagic stroke (HS) for 188 countries from 1990 to 2013. Methodology: Stroke incidence, prevalence, mortality, DALYs and YLDs were estimated using all available data on mortality and stroke incidence, prevalence and excess mortality. Statistical models and country-level covariate data were employed, and all rates were age-standardized to a global population. All estimates were produced with 95% uncertainty intervals (UIs). Results: In 2013, there were globally almost 25.7 million stroke survivors (71% with IS), 6.5 million deaths from stroke (51% died from IS), 113 million DALYs due to stroke (58% due to IS) and 10.3 million new strokes (67% IS). Over the 1990-2013 period, there was a significant increase in the absolute number of DALYs due to IS, and of deaths from IS and HS, survivors and incident events for both IS and HS. The preponderance of the burden of stroke continued to reside in developing countries, comprising 75.2% of deaths from stroke and 81.0% of stroke-related DALYs. Globally, the proportional contribution of stroke-related DALYs and deaths due to stroke compared to all diseases increased from 1990 (3.54% (95% UI 3.11-4.00) and 9.66% (95% UI 8.47-10.70), respectively) to 2013 (4.62% (95% UI 4.01-5.30) and 11.75% (95% UI 10.45-13.31), respectively), but there was a diverging trend in developed and developing countries with a significant increase in DALYs and deaths in developing countries, and no measurable change in the proportional contribution of DALYs and deaths from stroke in developed countries. Conclusion: Global stroke burden continues to increase globally. More efficient stroke prevention and management strategies are urgently needed to halt and eventually reverse the stroke pandemic, while universal access to organized stroke services should be a priority.
KW - GBD 2013
KW - Global burden
KW - Hemorrhagic stroke
KW - Ischemic stroke
KW - Stroke
UR - http://www.scopus.com/inward/record.url?scp=84946064513&partnerID=8YFLogxK
U2 - 10.1159/000441085
DO - 10.1159/000441085
M3 - Article
C2 - 26505981
AN - SCOPUS:84946064513
VL - 45
SP - 161
EP - 176
JO - Neuroepidemiology
JF - Neuroepidemiology
SN - 0251-5350
IS - 3
ER -