Use of a rapid faeces multiplex PCR assay for diagnosis of amoebic liver abscess

Nicholas M. Douglas, Robert W. Baird, Bart J. Currie

Research output: Contribution to journalLetterpeer-review

Abstract

Sir,
Entamoeba histolytica is an intestinal, protozoan parasite endemic to non-industrialised parts of Latin America, Africa and the Indian subcontinent. It causes an estimated 40,000–100,000 deaths each year, primarily from amoebic colitis and amoebic liver abscess (ALA).1 Although morphologically indistinguishable, strains of E. histolytica causing ALA often differ genetically from those causing colitis.2,3 Colonic carriage can also be asymptomatic, as is always the case for other apathogenic species such as E. dispar and E. moshkovskii. Therefore, clinical history of colitis or detection of Entamoeba in stool do not provide reliable clues for the diagnosis of ALA.

Original languageEnglish
Pages (from-to)725-727
Number of pages3
JournalPathology
Volume52
Issue number6
DOIs
Publication statusPublished - Oct 2020
Externally publishedYes

Keywords

  • Correspondence
  • Entamoeba histolytica
  • intestinal parasites
  • amoebic colitis
  • amoebic liver abscess (ALA)
  • colonic carriage

Fingerprint

Dive into the research topics of 'Use of a rapid faeces multiplex PCR assay for diagnosis of amoebic liver abscess'. Together they form a unique fingerprint.

Cite this