Uveitis in Juvenile Idiopathic Arthritis: Recent Therapeutic Advances

Jane M Wells, Justine R Smith

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)
19 Downloads (Pure)


Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment. Since corticosteroid treatment is not a preferred long-term option for most patients with this condition, systemic immunosuppressive therapy is frequently employed. The medical options for the treatment of JIA-associated uveitis have recently expanded beyond conventional immunosuppressive drugs to the biological agents. The biological drugs that are most commonly employed for JIA-associated uveitis are the tumor necrosis factor-α inhibitors. Other biological agents that have been used to treat the disease include drugs that target cytokine receptors, lymphocyte antigens and lymphocyte co-stimulation signals. This Mini Review highlights recent developments in the medical treatment of JIA-associated uveitis.

Original languageEnglish
Pages (from-to)124-127
Number of pages4
JournalOphthalmic Research
Issue number3
Publication statusPublished - Oct 2015


  • Uveitis
  • Juvenile idiopathic arthritis
  • Biological agents


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