Variables of patient‐controlled analgesia: 1. bolus size

H. OWEN, J. L. PLUMMER, I. ARMSTRONG, L. E. MATHER, M. J. COUSINS

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114 Citations (Scopus)

Abstract

The efficacy of a range of demand doses of morphine for patient‐controlled analgesia was studied. Patients who self–administered the smallest dose (0.5 mg) were frequently unable to achieve good pain control; patients who received the largest dose (2 mg) had a high incidence of ventilatory depression. A dose of 1 mg was the best increment under the conditions of this study but the relationship between increment and lockout interval requires consideration.

Original languageEnglish
Pages (from-to)7-10
Number of pages4
JournalAnaesthesia
Volume44
Issue number1
DOIs
Publication statusPublished - Jan 1989
Externally publishedYes

Keywords

  • Analgesia; on‐demand
  • Pain; postoperative

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