Variables of patient‐controlled analgesia. 3:: test of an infusion‐demand system using alfentanil

H. Owen; W. G. Brose; J. L. Plummer; L. E. Mather

doi:10.1111/j.1365-2044.1990.tb14332.x

Variables of patient‐controlled analgesia. 3: test of an infusion‐demand system using alfentanil

H. Owen, W. G. Brose, J. L. Plummer, L. E. Mather

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Abstract

Patient‐controlled infusion‐demand analgesia was studied using alfentanil. We were unable to identify an optimal dose and administration rate; doses required range from 100 to 900 μg alfentanil. The mean concentration of alfentanil in blood associated with return of pain (i.e. immediately before demand) was 58 ng/ml on day 1 and 37 ng/ml on day 2. This difference was despite similar drug consumption on both days.

Original language	English
Pages (from-to)	452-455
Number of pages	4
Journal	Anaesthesia
Volume	45
Issue number	6
DOIs	https://doi.org/10.1111/j.1365-2044.1990.tb14332.x
Publication status	Published - Jun 1990

Keywords

Analgesics, narcotic; alfentanil
Pain; postoperative

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Variables of patient‐controlled analgesia. 3: test of an infusion‐demand system using alfentanil

Abstract

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