Variables of patient‐controlled analgesia. 3: test of an infusion‐demand system using alfentanil

H. Owen, W. G. Brose, J. L. Plummer, L. E. Mather

    Research output: Contribution to journalArticle

    24 Citations (Scopus)

    Abstract

    Patient‐controlled infusion‐demand analgesia was studied using alfentanil. We were unable to identify an optimal dose and administration rate; doses required range from 100 to 900 μg alfentanil. The mean concentration of alfentanil in blood associated with return of pain (i.e. immediately before demand) was 58 ng/ml on day 1 and 37 ng/ml on day 2. This difference was despite similar drug consumption on both days.

    Original languageEnglish
    Pages (from-to)452-455
    Number of pages4
    JournalAnaesthesia
    Volume45
    Issue number6
    DOIs
    Publication statusPublished - Jun 1990

    Keywords

    • Analgesics, narcotic; alfentanil
    • Pain; postoperative

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