Variables of patient‐controlled analgesia 4:: the relevance of bolus dose size to supplement a background infusion

H. Owen; M. T. Kluger; J. L. Plummer

doi:10.1111/j.1365-2044.1990.tb14382.x

Variables of patient‐controlled analgesia 4: the relevance of bolus dose size to supplement a background infusion

H. Owen, M. T. Kluger, J. L. Plummer

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

A range of self‐administered demand doses of morphine (0.4, 0.7 and 1.0 mg) were prescribed to supplement a fixed‐rate infusion (1.5 mg/hour) for pain control after gynaecological surgery. The number of demand doses administered during the first 25 hours after surgery was not significantly influenced by size of demand dose. There was a significant linear trend to increasing amount of demanded morphine with increasing bolus size. These results cast doubt on the usefulness of the concept of a minimum effective analgesic concentration of morphine.

Original language	English
Pages (from-to)	619-622
Number of pages	4
Journal	Anaesthesia
Volume	45
Issue number	8
DOIs	https://doi.org/10.1111/j.1365-2044.1990.tb14382.x
Publication status	Published - Aug 1990

Keywords

Analgesia; on‐demand, patient‐controlled
Pain; postoperative

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Variables of patient‐controlled analgesia 4: the relevance of bolus dose size to supplement a background infusion

Abstract

Keywords

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