Voluntary exercise is neuroprotective in an inherited retinal degeneration mouse model

Adam Hanif; Eric Lawson; Megan Prunty; Marissa Gogniat; Moe Hein Aung; Ranjay Chakraborty; Micah A. Chrenek; Jeffrey H. Boatright; Machelle T. Pardue

Voluntary exercise is neuroprotective in an inherited retinal degeneration mouse model

Adam Hanif, Eric Lawson, Megan Prunty, Marissa Gogniat, Moe Hein Aung, Ranjay Chakraborty, Micah A. Chrenek, Jeffrey H. Boatright, Machelle T. Pardue

Research output: Contribution to conference › Paper › peer-review

Abstract

Our previous investigations demonstrated that forced exercise provides BDNF-mediated neuroprotection in a light damage model of retinal injury (Lawson et al., J Neurosci 2014). In this study, we hypothesized that voluntary running wheel exercise would preserve retinal structure and function through this same BDNF pathway in the rd10 model of retinitis pigmentosa (RP).

Original language	English
Number of pages	1
Publication status	Published - Jun 2015
Externally published	Yes
Event	The Association for Research in Vision and Ophthalmology annual meeting 2012 - Fort Lauderdale Convention Center, Fort Lauderdale, United States Duration: 6 May 2012 → 10 May 2012 Conference number: 14

Conference

Conference	The Association for Research in Vision and Ophthalmology annual meeting 2012
Abbreviated title	ARVO 2012
Country/Territory	United States
City	Fort Lauderdale
Period	6/05/12 → 10/05/12

Keywords

retinal degeneration
mice
deprivation myopia

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Hanif, A., Lawson, E., Prunty, M., Gogniat, M., Aung, M. H., Chakraborty, R., Chrenek, M. A., Boatright, J. H., & Pardue, M. T. (2015). Voluntary exercise is neuroprotective in an inherited retinal degeneration mouse model. Paper presented at The Association for Research in Vision and Ophthalmology annual meeting 2012, Fort Lauderdale, Florida, United States. https://iovs.arvojournals.org/article.aspx?articleid=2334302&resultClick=1

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title = "Voluntary exercise is neuroprotective in an inherited retinal degeneration mouse model",

abstract = "Our previous investigations demonstrated that forced exercise provides BDNF-mediated neuroprotection in a light damage model of retinal injury (Lawson et al., J Neurosci 2014). In this study, we hypothesized that voluntary running wheel exercise would preserve retinal structure and function through this same BDNF pathway in the rd10 model of retinitis pigmentosa (RP).",

keywords = "retinal degeneration, mice, deprivation myopia",

author = "Adam Hanif and Eric Lawson and Megan Prunty and Marissa Gogniat and Aung, {Moe Hein} and Ranjay Chakraborty and Chrenek, {Micah A.} and Boatright, {Jeffrey H.} and Pardue, {Machelle T.}",

year = "2015",

month = jun,

language = "English",

note = "The Association for Research in Vision and Ophthalmology annual meeting 2012, ARVO 2012 ; Conference date: 06-05-2012 Through 10-05-2012",

}

Hanif, A, Lawson, E, Prunty, M, Gogniat, M, Aung, MH, Chakraborty, R, Chrenek, MA, Boatright, JH & Pardue, MT 2015, 'Voluntary exercise is neuroprotective in an inherited retinal degeneration mouse model', Paper presented at The Association for Research in Vision and Ophthalmology annual meeting 2012, Fort Lauderdale, United States, 6/05/12 - 10/05/12. <https://iovs.arvojournals.org/article.aspx?articleid=2334302&resultClick=1>

TY - CONF

T1 - Voluntary exercise is neuroprotective in an inherited retinal degeneration mouse model

AU - Hanif, Adam

AU - Lawson, Eric

AU - Prunty, Megan

AU - Gogniat, Marissa

AU - Aung, Moe Hein

AU - Chakraborty, Ranjay

AU - Chrenek, Micah A.

AU - Boatright, Jeffrey H.

AU - Pardue, Machelle T.

N1 - Conference code: 14

PY - 2015/6

Y1 - 2015/6

N2 - Our previous investigations demonstrated that forced exercise provides BDNF-mediated neuroprotection in a light damage model of retinal injury (Lawson et al., J Neurosci 2014). In this study, we hypothesized that voluntary running wheel exercise would preserve retinal structure and function through this same BDNF pathway in the rd10 model of retinitis pigmentosa (RP).

AB - Our previous investigations demonstrated that forced exercise provides BDNF-mediated neuroprotection in a light damage model of retinal injury (Lawson et al., J Neurosci 2014). In this study, we hypothesized that voluntary running wheel exercise would preserve retinal structure and function through this same BDNF pathway in the rd10 model of retinitis pigmentosa (RP).

KW - retinal degeneration

KW - mice

KW - deprivation myopia

M3 - Paper

T2 - The Association for Research in Vision and Ophthalmology annual meeting 2012

Y2 - 6 May 2012 through 10 May 2012

ER -

Voluntary exercise is neuroprotective in an inherited retinal degeneration mouse model

Abstract

Conference

Keywords

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