Vortex fluidic promoted Diels-Alder reactions in an aqueous medium

Lyzu Yasmin; Keith Stubbs; Colin Raston

doi:10.1016/j.tetlet.2014.02.077

Vortex fluidic promoted Diels-Alder reactions in an aqueous medium

Lyzu Yasmin, Keith Stubbs, Colin Raston

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

'Soft energy' provided within a thin film microfluidic platform, namely a vortex fluidic device (VFD), is effective in accelerating and promoting Diels-Alder reactions in the absence of any catalyst. Diels-Alder cycloadducts generated from different 9-substituted anthracenes and N-maleimides are formed in high yield in an aqueous medium using the confined mode of operation of the VFD.

Original language	English
Pages (from-to)	2246-2248
Number of pages	3
Journal	Tetrahedron Letters
Volume	55
Issue number	14
DOIs	https://doi.org/10.1016/j.tetlet.2014.02.077
Publication status	Published - 2 Apr 2014

Keywords

9-Substituted anthracenes
Diels-Alder cycloaddition
N-maleimides
Thin film microfluidics
Vortex fluidics

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10.1016/j.tetlet.2014.02.077

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abstract = "'Soft energy' provided within a thin film microfluidic platform, namely a vortex fluidic device (VFD), is effective in accelerating and promoting Diels-Alder reactions in the absence of any catalyst. Diels-Alder cycloadducts generated from different 9-substituted anthracenes and N-maleimides are formed in high yield in an aqueous medium using the confined mode of operation of the VFD.",

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AU - Raston, Colin

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KW - Diels-Alder cycloaddition

KW - N-maleimides

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