Vortex fluidic promoted Diels-Alder reactions in an aqueous medium

Lyzu Yasmin, Keith Stubbs, Colin Raston

    Research output: Contribution to journalArticlepeer-review

    25 Citations (Scopus)


    'Soft energy' provided within a thin film microfluidic platform, namely a vortex fluidic device (VFD), is effective in accelerating and promoting Diels-Alder reactions in the absence of any catalyst. Diels-Alder cycloadducts generated from different 9-substituted anthracenes and N-maleimides are formed in high yield in an aqueous medium using the confined mode of operation of the VFD.

    Original languageEnglish
    Pages (from-to)2246-2248
    Number of pages3
    JournalTetrahedron Letters
    Issue number14
    Publication statusPublished - 2 Apr 2014


    • 9-Substituted anthracenes
    • Diels-Alder cycloaddition
    • N-maleimides
    • Thin film microfluidics
    • Vortex fluidics


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