Whole-genome sequencing to differentiate relapse from reinfection in community-onset bacteremic acinetobacter baumannii pneumonia

Ella M. Meumann, Nicholas M. Anstey, Bart J. Currie, Kim A. Piera, Robert Baird, Derek S. Sarovich, Joshua S. Davis

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Community-onset bacteremic Acinetobacter baumannii pneumonia recurred in 3 of 30 (10%) patients followed prospectively, all with ongoing hazardous alcohol intake, 3 56 months after initial pneumonia. Paired isolates underwent whole-genome sequencing. Phylogenetic analysis showed that recurrence strains were all distinct from preceding strains, indicating reinfection in susceptible individuals rather than relapse.

Original languageEnglish
Article numberofz263
Number of pages4
JournalOpen Forum Infectious Diseases
Volume6
Issue number7
DOIs
Publication statusPublished - Jul 2019
Externally publishedYes

Keywords

  • Acinetobacter baumannii
  • Community-Acquired pneumonia
  • Recurrence
  • Relapse
  • Whole-genome sequencing.

Fingerprint

Dive into the research topics of 'Whole-genome sequencing to differentiate relapse from reinfection in community-onset bacteremic acinetobacter baumannii pneumonia'. Together they form a unique fingerprint.

Cite this