Research output per year
Research output per year
Personal profile
Research Biography
I am a Health AI researcher, biostatistician, and pharmacist with over 20 years of experience applying data science and artificial intelligence to improve the use of medicines and healthcare decision-making.
My research spans three main areas:
- developing and critically evaluating health applications of generative AI, with a focus on clinical reliability, safety, and oversight
- using machine learning and advanced biostatistical methods - often with individual participant data from clinical trials - to predict who will benefit from anti-cancer treatments and who is at risk of serious side effects.
- investigating extracellular vesicle biomarkers as liquid biopsies to track drug effects on specific organs in real time.
With extensive expertise in clinical data science - including agentic AI, predictive AI, survival analysis, treatment effect modification, clinical trial evaluation, and meta-analysis - I aim to understand and utilise complex data to improve healthcare. I welcome opportunities for collaboration to advance healthcare through innovative research and education.
Research Interests
- Health applications of artificial intelligence
- Precision medicine
- Machine learning methods
- Predicting therapeutic and adverse outcomes of cancer medicines in advanced cancer
- Novel biomarkers for precision dosing of medicines
- Evidence-based medicine, clinical epidemiology, pharmacometrics, decision analysis, pharmacoeconomics and meta-analysis
Supervision
- Registered
Research Areas
- Knowledge discovery, AI and data mining
- Digital health and technology
Supervisory Interests
- Generative artificial intelligence
- Clinical epidemiology
- Personalised medicine
- Biomarkers
- Machine learning
- Biostatistics
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities -
SDG 16 Peace, Justice and Strong Institutions
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized controlled trials
Sorich, M., Wiese, M., Rowland, A., Kichenadasse, G., McKinnon, R. & Karapetis, C., 1 Jan 2015, In: Annals of Oncology. 26, 1, p. 13-21 9 p.Research output: Contribution to journal › Review article › peer-review
465 Citations (Scopus) -
Association between body mass index and overall survival with immune checkpoint inhibitor therapy for advanced non-small cell lung cancer
Kichenadasse, G., Miners, J. O., Mangoni, A. A., Rowland, A., Hopkins, A. M. & Sorich, M. J., Apr 2020, In: JAMA Oncology. 6, 4, p. 512-518 7 p.Research output: Contribution to journal › Article › peer-review
295 Citations (Scopus) -
Health Disinformation Use Case Highlighting the Urgent Need for Artificial Intelligence Vigilance: Weapons of Mass Disinformation
Menz, B. D., Modi, N. D., Sorich, M. J. & Hopkins, A. M., 2 Jan 2024, In: JAMA Internal Medicine. 184, 1, p. 92-96 5 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile93 Citations (Scopus)191 Downloads (Pure) -
Plasma extracellular nanovesicle (exosome)-derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure
Rowland, A., Ruanglertboon, W., Van Dyk, M., Wijayakumara, D. D., Wood, L. S., Meech, R., Mackenzie, P. I., Rodrigues, A. D., Marshall, J. C. & Sorich, M. J., 1 Jan 2019, In: British Journal of Clinical Pharmacology. 85, 1, p. 216-226 11 p.Research output: Contribution to journal › Article › peer-review
Open Access76 Citations (Scopus) -
Audit of Data Sharing by Pharmaceutical Companies for Anticancer Medicines Approved by the US Food and Drug Administration
Modi, N. D., Abuhelwa, A. Y., McKinnon, R. A., Boddy, A. V., Haseloff, M., Wiese, M. D., Hoffmann, T. C., Perakslis, E. D., Rowland, A., Sorich, M. J. & Hopkins, A. M., Sept 2022, In: JAMA Oncology. 8, 9, p. 1310-1316 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)89 Downloads (Pure)
Projects
- 1 Active
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A Comprehensive ADME Genomic Profile to Enhance Safety and Reduce Medicine Harms
Rowland, A. (Chief Investigator (Project Lead)), Westley, I. (Chief Investigator), Kichenadasse, G. (Chief Investigator), Sorich, M. (Chief Investigator), Newman, L. (Chief Investigator), Ross, D. (Chief Investigator), Branford, S. (Chief Investigator), Scott, H. (Chief Investigator), Hopkins, A. (Chief Investigator), Karapetis, C. (Chief Investigator), Guchelaar, H. J. (Chief Investigator), To, T. (Chief Investigator), Karnon, J. (Chief Investigator) & Haseloff, M. (Associate Investigator)
1/06/25 → 31/05/28
Project: Research
Activities
- 1 Other
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Pharmacogenomics, Australian Pharmaceutical Formulary
Haddy, C. A. (Participant), McKinnon, R. (Participant), Sorich, M. (Participant) & Ward, M. (Participant)
2006 → …Activity: Other activity types › Other